Friday, February 24, 2012

But at 1 and 6 months, there were no differences ...

After the feasibility study shows that minimally invasive procedure for treatment of severe emphysema can alleviate symptoms, the researchers hoped a large randomized controlled trial would confirm that this approach was effective. But hope turned to disappointment, because


from the International Court, published today in the


The Lancet, showed that the procedure does not provide a sustainable advantage. Emphysema the drug lasix is a chronic and progressive disease that mainly the result of prolonged exposure to air irritants such as tobacco smoke and air pollution. In the tissues that support the form and function of the lungs are destroyed, patients have difficulty forcing air from their lungs that hinders breathing. There are several options for treatment and no cure for emphysema, which affects about 6000000 people worldwide. The study, which involved 315 patients with emphysema who were treated in 38 centers specializing in lung diseases, the researchers used a bronchoscope to gain access to the airway and perform airway bypass procedure in 208 patients. This procedure includes the creation of 14 small passages between the damaged tissue of the lungs and airways to release trapped air and insert stents to 6 small new ways to keep open. Such intervention, the researchers hoped that considerably reduce the amount of air remaining in lungs after full exhalation, helping to relieve breathlessness. The remaining 107 study participants received a sham procedure in which the bronchoscope was inserted, but the passages were made and no stents were placed. The next day after the procedure, improve breathing for study patients who underwent airway bypass, they have less air bubbles to the lungs and were able to inhale and exhale more deeply in comparison with those procedures deception. But at 1 and 6 months, there were no differences in symptoms between the 2 groups. Researchers have suggested that life again opened the passages of the lungs may have played a role in the disappointing results, noting that not all passes received stents and some stents were blocked with mucus. .

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